Sertraline (Zoloft)
One of the most commonly prescribed antidepressants in the US. Sertraline increases serotonin in the brain to help stabilise mood and reduce anxiety. Most people begin to notice changes within 2–4 weeks.
Most patients pay less than $30 per appointment.
Sertraline is often prescribed as part of a comprehensive treatment plan that may include therapy. It helps regulate brain activity to support improved mood and daily functioning — making life more manageable for people living with depression, anxiety, and related conditions.
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Komal Nathani
Komal is an LGBTQ+ affirming psychiatrist who works with queer, trans, and gender-expansive adolescents and adults navigating anxiety, depression, ADHD, trauma, and identity. She offers a space where your full self is welcome, and brings real understanding to the intersection of queerness, culture, and mental health.
MD Psychiatrist
Adam Butera
Adam is an LGBTQ+ affirming psychiatrist with 23 years in private practice, offering care for depression, bipolar disorder, anxiety, PTSD, OCD, addiction, and ADHD. He takes time to understand each person as a whole human being, working with adolescents, adults, and seniors across diverse backgrounds.
MD PsychiatristReal Questions. Honest Answers.
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Sertraline treats depression, anxiety, panic disorder, PTSD, OCD, and PMDD. It is one of the most widely prescribed medications in its class and has one of the longest safety track records of any antidepressant.
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Most people begin to notice changes within 2–4 weeks. Full effects are typically felt around 6–8 weeks. Your psychiatrist may adjust your dose during this period.
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Common early side effects include nausea, headache, and trouble sleeping. These usually fade as your body adjusts. Sexual side effects and mild weight changes may persist for some people
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No — stopping sertraline suddenly can cause withdrawal symptoms such as dizziness, irritability, and flu-like feelings. Always taper with your doctor's guidance.
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Some people notice mild weight changes, particularly with long-term use. This varies by person. Talk to your psychiatrist if weight is a concern — alternatives exist.
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It is best to avoid or significantly limit alcohol. Both sertraline and alcohol affect serotonin, and combining them can increase side effects like drowsiness and dizziness.
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Sertraline is available as an inexpensive generic and is covered by most major insurance plans, including all plans we accept at Outspace. Most patients pay as little as $20 per appointment.
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Book a free consultation at Outspace. One of our licensed psychiatrists will evaluate whether sertraline is the right fit for you — and if so, issue a prescription that day.