Seroquel
(Quetiapine)
Seroquel is an atypical antipsychotic used to treat bipolar disorder, schizophrenia, and major depression as an add-on. At lower doses it is also commonly prescribed for sleep and anxiety, though these are off-label uses.
Most patients pay less than $20 per appointment.
Seroquel works by affecting dopamine and serotonin receptors in the brain. Its active ingredient, quetiapine, is a versatile medication used across a spectrum of psychiatric conditions and is often added to an antidepressant when a first medication alone is not providing full relief.
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Komal Nathani
Komal is an LGBTQ+ affirming psychiatrist who works with queer, trans, and gender-expansive adolescents and adults navigating anxiety, depression, ADHD, trauma, and identity. She offers a space where your full self is welcome, and brings real understanding to the intersection of queerness, culture, and mental health.
MD Psychiatrist
Adam Butera
Adam is an LGBTQ+ affirming psychiatrist with 23 years in private practice, offering care for depression, bipolar disorder, anxiety, PTSD, OCD, addiction, and ADHD. He takes time to understand each person as a whole human being, working with adolescents, adults, and seniors across diverse backgrounds.
MD PsychiatristReal questions. Honest answers.
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Seroquel (quetiapine) is FDA-approved for schizophrenia, bipolar disorder (manic and depressive episodes), and as an add-on for major depression. At low doses it is frequently used off-label for insomnia and anxiety.
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At low doses (25–100mg), Seroquel has a sedating effect. While not FDA-approved for this purpose, psychiatrists sometimes prescribe it short-term for insomnia when other medications have not worked.
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Sedation, weight gain, dry mouth, constipation, and dizziness are common. Metabolic changes (blood sugar, cholesterol) should be monitored with long-term use.
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It can — particularly at higher doses. Your psychiatrist will monitor your weight and metabolic health and may recommend dietary adjustments.
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Seroquel is not considered addictive in the way benzodiazepines are, but it should not be stopped abruptly — withdrawal symptoms such as insomnia and nausea can occur.
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Yes, many people take it long-term safely. Regular monitoring of metabolic markers (glucose, cholesterol, weight) is important.
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For sleep and acute mania, effects are usually felt quickly. For depression and anxiety, improvement typically takes 2–4 weeks.
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Book a free consult at Outspace. Our psychiatrists will assess your full history and determine whether Seroquel is appropriate for your needs.