Remeron
(Mirtazapine)
Remeron is an antidepressant with a unique mechanism that also improves sleep, stimulates appetite, and reduces nausea. It is especially helpful for people with depression accompanied by weight loss, poor sleep, or significant anxiety.
Most patients pay less than $20 per appointment.
Remeron works by blocking certain receptors that normally suppress serotonin and norepinephrine release. Its sedating and appetite-stimulating effects — strongest at lower doses — make it particularly useful for people who are underweight, struggling to sleep, or experiencing nausea alongside their depression.
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Board-certified psychiatrists with deep expertise in LGBTQ+ mental health and medication management.
Komal Nathani
Komal is an LGBTQ+ affirming psychiatrist who works with queer, trans, and gender-expansive adolescents and adults navigating anxiety, depression, ADHD, trauma, and identity. She offers a space where your full self is welcome, and brings real understanding to the intersection of queerness, culture, and mental health.
MD Psychiatrist
Adam Butera
Adam is an LGBTQ+ affirming psychiatrist with 23 years in private practice, offering care for depression, bipolar disorder, anxiety, PTSD, OCD, addiction, and ADHD. He takes time to understand each person as a whole human being, working with adolescents, adults, and seniors across diverse backgrounds.
MD PsychiatristReal questions. Honest answers.
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Remeron (mirtazapine) is FDA-approved for major depression. It is also widely used off-label for anxiety, insomnia, appetite stimulation, and nausea — often in palliative or cancer care.
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Yes — increased appetite and weight gain are common, particularly at lower doses. This can be a benefit for people who have lost weight due to depression, or a drawback for others.
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At low doses (7.5–15mg), Remeron's sedating antihistamine effects dominate. At higher doses, norepinephrine activation partially counteracts the sedation, making it less sleep-inducing.
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Sedation, increased appetite, weight gain, dry mouth, and constipation are most common. Most people find sedation helpful at bedtime.
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Yes — Remeron has notable anti-anxiety properties and is often chosen when someone needs relief from both depression and significant anxiety or panic.
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It can interact with MAOIs and certain other antidepressants. Share your full medication list with your psychiatrist.
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Sleep and appetite improvements are often noticed within the first 1–2 weeks. Full antidepressant effects typically take 4–6 weeks.
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Book a free consult at Outspace. Our psychiatrists will assess whether Remeron suits your full symptom picture.