Prozac
(Fluoxetine)
Prozac is one of the most recognised antidepressants in the world. The active ingredient, fluoxetine, was among the first SSRIs approved by the FDA and has decades of safety data behind it. It is effective for depression, OCD, bulimia, and panic disorder.
Most patients pay less than $30 per appointment.
Prozac has a longer half-life than most SSRIs, which means it stays in your system longer and discontinuation is generally smoother. It is frequently paired with therapy and is a common first choice for adolescents and adults alike.
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Komal Nathani
Komal is an LGBTQ+ affirming psychiatrist who works with queer, trans, and gender-expansive adolescents and adults navigating anxiety, depression, ADHD, trauma, and identity. She offers a space where your full self is welcome, and brings real understanding to the intersection of queerness, culture, and mental health.
MD PsychiatristAdam Butera
Adam is an LGBTQ+ affirming psychiatrist with 23 years in private practice, offering care for depression, bipolar disorder, anxiety, PTSD, OCD, addiction, and ADHD. He takes time to understand each person as a whole human being, working with adolescents, adults, and seniors across diverse backgrounds.
MD PsychiatristReal Questions. Honest Answers.
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Prozac (fluoxetine) is FDA-approved for depression, OCD, panic disorder, bulimia nervosa, bipolar depression (with a mood stabiliser), and PMDD.
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Prozac and its active metabolite stay in the body for 1–4 weeks after stopping. This makes discontinuation easier but also means it takes longer to clear your system if a change is needed.
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Most people notice early improvements in sleep and energy within 1–2 weeks, with full antidepressant effects by week 4–6.
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Nausea, insomnia, headache, and reduced appetite are common early on. These tend to improve after the first few weeks.
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Some people feel slightly more anxious in the first week or two. This typically passes. Starting at a low dose helps minimise this effect.
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Yes — Prozac inhibits certain liver enzymes and can raise the levels of other drugs in your system. Share your full medication list with your psychiatrist.
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Prozac is one of the few antidepressants FDA-approved for use in children and adolescents for depression and OCD. A psychiatrist will monitor closely, especially in the early weeks.
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Book a free consult. Our psychiatrists will review your history and determine whether Prozac is a good fit for you.