Abilify
(Aripiprazole)
Abilify is an atypical antipsychotic that partially activates dopamine receptors rather than simply blocking them. It is used for bipolar disorder, schizophrenia, and as an add-on for depression, and is generally better tolerated than older antipsychotics.
Most patients pay less than $20 per appointment.
Abilify is often chosen when weight gain or sedation from other antipsychotics is a concern. Its unique mechanism — partial agonism at dopamine receptors — gives it a different side effect profile compared to most antipsychotics, making it well-suited to long-term use.
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Komal Nathani
Komal is an LGBTQ+ affirming psychiatrist who works with queer, trans, and gender-expansive adolescents and adults navigating anxiety, depression, ADHD, trauma, and identity. She offers a space where your full self is welcome, and brings real understanding to the intersection of queerness, culture, and mental health.
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Adam Butera
Adam is an LGBTQ+ affirming psychiatrist with 23 years in private practice, offering care for depression, bipolar disorder, anxiety, PTSD, OCD, addiction, and ADHD. He takes time to understand each person as a whole human being, working with adolescents, adults, and seniors across diverse backgrounds.
MD PsychiatristReal questions. Honest answers.
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Abilify (aripiprazole) is FDA-approved for schizophrenia, bipolar I disorder, as an adjunct for major depression, irritability in autism, and Tourette's disorder.
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Most antipsychotics block dopamine receptors. Abilify partially activates them — a subtler action that tends to cause less sedation and less weight gain than many alternatives.
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It can cause some weight gain, but generally less than many other antipsychotics. Metabolic monitoring is still recommended.
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Restlessness (akathisia), headache, nausea, insomnia, and constipation. Akathisia — an uncomfortable urge to move — can be distressing but is manageable with dose adjustment.
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Yes — unlike many antipsychotics, Abilify can feel stimulating rather than sedating. For some people this is welcome; for others it can cause insomnia or restlessness.
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Yes, with regular monitoring. Your psychiatrist will check for metabolic changes and movement-related side effects at routine appointments.
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For acute symptoms of mania or psychosis, some improvement is typically seen within 1–2 weeks. Full stabilisation may take 4–6 weeks.
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Book a free consult. Our psychiatrists will assess your history and determine whether Abilify is the right addition to your care plan.